What is Botox for migraine?

OnabotulinomtoxinA (Botox) is an effective and safe treatment for the prevention of chronic migraine in adults. Botox for chronic migraine (PREEMPT protocol) is administered with a very small needle to 31 areas of muscle around the face, head, neck and shoulders every 12 weeks. The most common reported adverse side effects from the PREEMPT studies were neck pain (6.7%), muscular weakness (5.5%), eyelid ptosis (droopiness) (3.3%), and injection site pain (3.2%). Most reported adverse events were mild to moderate in severity. 

A retrospective clinical study that was performed by Dr. Soh at the Hartford Healthcare Headache Center found that more than 50% of patients had a greater than 50% reduction in headache days per month after receiving Botox at six- and nine-months post-treatment. This retrospective study examined adults who were 65 and older.